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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL14
All Species:
5.76
Human Site:
S309
Identified Species:
11.52
UniProt:
Q8N1E6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N1E6
NP_689654.1
418
45886
S309
Q
G
L
D
G
L
K
S
L
S
L
C
S
C
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117874
404
44252
A298
K
V
G
D
Q
S
L
A
Y
I
A
Q
G
L
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BID8
400
43846
D294
S
F
C
D
K
V
G
D
Q
S
L
A
Y
I
A
Rat
Rattus norvegicus
Q5MJ12
479
51833
N314
I
T
N
H
G
V
V
N
V
V
H
S
L
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425498
333
36281
D227
S
F
C
D
K
V
G
D
Q
S
L
A
Y
I
A
Frog
Xenopus laevis
NP_001083845
400
43783
D294
S
F
C
D
K
V
G
D
Q
S
L
A
Y
I
A
Zebra Danio
Brachydanio rerio
NP_001015043
400
44429
D294
S
F
C
D
K
I
G
D
Q
S
L
A
Y
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523812
538
58367
S427
E
G
G
S
G
I
N
S
L
D
V
S
F
C
D
Honey Bee
Apis mellifera
XP_393659
481
52936
S370
E
G
G
S
R
I
S
S
L
D
V
S
F
C
D
Nematode Worm
Caenorhab. elegans
P34284
466
52046
V309
Q
H
S
H
N
L
K
V
L
E
L
S
G
C
T
Sea Urchin
Strong. purpuratus
XP_784778
450
49952
T339
E
Y
G
G
H
F
A
T
L
D
A
S
F
C
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5D2
610
66404
R350
H
G
C
K
E
L
E
R
V
E
I
N
G
C
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
N.A.
N.A.
95.6
21.2
N.A.
N.A.
75.5
90.6
88.7
N.A.
46.2
54
25.5
63.5
Protein Similarity:
100
N.A.
96.6
N.A.
N.A.
95.6
37.1
N.A.
N.A.
77.9
93
92.1
N.A.
58.3
65.9
43.1
73.3
P-Site Identity:
100
N.A.
6.6
N.A.
N.A.
20
6.6
N.A.
N.A.
20
20
20
N.A.
33.3
26.6
40
13.3
P-Site Similarity:
100
N.A.
20
N.A.
N.A.
26.6
33.3
N.A.
N.A.
26.6
26.6
26.6
N.A.
53.3
46.6
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
26
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
9
0
0
17
34
0
0
34
% A
% Cys:
0
0
42
0
0
0
0
0
0
0
0
9
0
50
0
% C
% Asp:
0
0
0
50
0
0
0
34
0
25
0
0
0
0
34
% D
% Glu:
25
0
0
0
9
0
9
0
0
17
0
0
0
0
0
% E
% Phe:
0
34
0
0
0
9
0
0
0
0
0
0
25
0
0
% F
% Gly:
0
34
34
9
25
0
34
0
0
0
0
0
25
0
0
% G
% His:
9
9
0
17
9
0
0
0
0
0
9
0
0
0
17
% H
% Ile:
9
0
0
0
0
25
0
0
0
9
9
0
0
34
0
% I
% Lys:
9
0
0
9
34
0
17
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
0
25
9
0
42
0
50
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
9
9
0
0
0
9
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
17
0
0
0
9
0
0
0
34
0
0
9
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
34
0
9
17
0
9
9
25
0
42
0
42
9
0
0
% S
% Thr:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
9
% T
% Val:
0
9
0
0
0
34
9
9
17
9
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
9
0
0
0
34
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _